Biering-Sørensen F
Clinic for Spinal Cord Injuries, Rigshospitalet, Copenhagen University Hospital, Havnevej, Hornbaek, Denmark.
Spinal Cord. 2005 Oct;43(10):587-92. doi: 10.1038/sj.sc.3101815.
The interest for evidence-based medicine (EBM) has grown, due to the enormous and exponentially increasing amount of medical literature published. EBM is 'the integration of best research evidence with clinical expertise and patient values'. The steps in the EBM process are (1) convert the need for information into a question; (2) find the best evidence; (3) critically evaluate the evidence; (4) integrate the critical appraisal with clinical expertise and the patient's unique biology, values, and circumstances; (5) evaluate the process and seek ways to improve effectiveness and efficiency. Both limitations related to the accumulation of evidence and the use and possible misuse of EBM in the health care are important to be aware of in the daily clinical environment. For use of EMB in treatment and rehabilitation of spinal cord injury MEDLINE is the most sensitive source for evidence due to its comprehensiveness and up to date maintenance, and the best pre-appraised evidence source is the Cochrane Library and Best Evidence. Clinical Practice Guidelines may provide a good summary of the actual evidence. In spite of limitations and dangers related to EMB, health care professionals generally agree that they should strive to incorporate evidence-based interventions into the multifaceted clinical decision-making process, including the individual patient values and circumstances.