McNeill R E, Diskin M G, Sreenan J M, Morris D G
Animal Reproduction Department, Teagasc Research Centre, Athenry, Co. Galway, Ireland.
Theriogenology. 2006 Apr 15;65(7):1435-41. doi: 10.1016/j.theriogenology.2005.08.015. Epub 2005 Oct 3.
The relationships between the concentration of milk progesterone and early embryo survival on Days 4-8 inclusive and between the concentration of progesterone on different days from Days 0-8 inclusive following ovulation and insemination were examined in dairy cows. The relationships were examined following 77 randomly chosen artificial inseminations to cows in standing oestrus. There was a significant (P < 0.05) linear and quadratic relationship between the concentration of milk progesterone on each of Days 4-6 after ovulation and the probability of embryo survival. There was no association (P > 0.05) between milk progesterone concentration and probability of embryo survival on Days 7 and 8 after ovulation. There were no associations between milk progesterone concentration on Days 0-2 and the concentrations on Days 4-7, however, progesterone concentrations on Days 4 and 5 were highly predictive of the concentration on Days 6 and 7, respectively. Overall, the results indicate that suboptimal progesterone support during the early luteal phase is likely to deleteriously affect embryo viability and in addition, that it is possible to predict milk progesterone concentrations during the early luteal phase based on earlier stage concentrations and thus identify cows at risk of early embryo loss.
在奶牛中，研究了排卵后第4至8天（含第4天和第8天）牛奶孕酮浓度与早期胚胎存活之间的关系，以及排卵和授精后第0至8天（含第0天和第8天）不同日期的孕酮浓度之间的关系。对77头处于发情期站立状态的奶牛进行随机人工授精后，对这些关系进行了研究。排卵后第4至6天的每一天，牛奶孕酮浓度与胚胎存活概率之间存在显著（P < 0.05）的线性和二次关系。排卵后第7天和第8天，牛奶孕酮浓度与胚胎存活概率之间没有关联（P > 0.05）。排卵后第0至2天的牛奶孕酮浓度与第4至7天的浓度之间没有关联，然而，第4天和第5天的孕酮浓度分别高度预测了第6天和第7天的浓度。总体而言，结果表明，黄体早期孕酮支持不足可能会对胚胎活力产生有害影响，此外，根据早期阶段的浓度可以预测黄体早期的牛奶孕酮浓度，从而识别有早期胚胎丢失风险的奶牛。
