St Amand Allison L, Frank Daniel N, De Groote Mary Ann, Basaraba Randall J, Orme Ian M, Pace Norman R
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309-0347, USA.
J Clin Microbiol. 2005 Oct;43(10):5369-71. doi: 10.1128/JCM.43.10.5369-5371.2005.
Mycobacterium tuberculosis infections are a major global health problem. Fast and accurate detection of M. tuberculosis is clearly needed at both the clinical level and the research level. We report a rapid and reliable in situ hybridization technique using rRNA oligonucleotide probes for the identification of M. tuberculosis in tissues and cultures.
结核分枝杆菌感染是一个重大的全球健康问题。显然,在临床和研究层面都需要快速、准确地检测结核分枝杆菌。我们报告了一种使用rRNA寡核苷酸探针在组织和培养物中鉴定结核分枝杆菌的快速且可靠的原位杂交技术。