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用于骨髓移植患者的痛苦温度计的验证。

Validation of the Distress Thermometer with bone marrow transplant patients.

作者信息

Ransom Sean, Jacobsen Paul B, Booth-Jones Margaret

机构信息

University of South Florida, USA.

出版信息

Psychooncology. 2006 Jul;15(7):604-12. doi: 10.1002/pon.993.

DOI:10.1002/pon.993
PMID:16208733
Abstract

The Distress Thermometer (DT) is a one-item screening measure of psychological distress in cancer patients. This study examines the operating characteristics of the DT in patients about to undergo bone marrow transplant (BMT). Patients (N=491) completed the DT, the Center for Epidemiological Studies-Depression Scale (CES-D), the State-Trait Anxiety Inventory-State Version (STAI-S), the ECOG Performance Status Scale, and the Patient Problem List. DT scores were related to higher depression, higher anxiety, and poorer performance status. Receiver operating characteristic (ROC) curve analyses of DT scores yielded area under the curve estimates of 0.75 when compared to the CES-D cutoff score of 16, suggesting the DT has acceptable overall accuracy. The DT cutoff score of 4 had the greatest sensitivity and specificity when compared to the CES-D cutoff score. Patients above this cutoff score reported worse ECOG scores and more practical, family, emotional, and physical problems (all p's< or =0.05) than those below the cutoff. The findings suggest the DT is a useful tool for screening for distress in BMT patients. The optimal DT cutoff score of 4 found here was identical to that found in another study using different criteria. This cutoff score also identified patients with problems likely to reflect psychological distress.

摘要

苦恼温度计(DT)是一种用于筛查癌症患者心理苦恼的单项测量工具。本研究考察了DT在即将接受骨髓移植(BMT)患者中的应用特征。患者(N = 491)完成了DT、流行病学研究中心抑郁量表(CES - D)、状态 - 特质焦虑量表 - 状态版(STAI - S)、东部肿瘤协作组(ECOG)体能状态量表以及患者问题清单。DT得分与更高的抑郁、更高的焦虑以及更差的体能状态相关。与CES - D临界值16相比,DT得分的受试者工作特征(ROC)曲线分析得出曲线下面积估计值为0.75,表明DT具有可接受的总体准确性。与CES - D临界值相比,DT临界值4具有最高的敏感性和特异性。高于此临界值的患者报告出比低于临界值的患者更差的ECOG得分以及更多实际、家庭、情感和身体问题(所有p值≤0.05)。研究结果表明DT是筛查BMT患者苦恼情况的有用工具。此处发现的DT最佳临界值4与另一项使用不同标准研究中发现的相同。这个临界值还识别出了可能反映心理苦恼问题的患者。

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