Yamauchi K, Omata T
Department of Internal Medicine, Tokai University School of Medicine, Kanagawa, Japan.
Respiration. 1992;59(2):119-21. doi: 10.1159/000196040.
We report the case of a 69-year-old man with chronic myelomonocytic leukemia (CMML) that was complicated by fatal respiratory failure. Bilateral pulmonary infiltrates were demonstrated by chest roentgenograms and worsened with an increase in the leukocyte count. Postmortem examination confirmed the presence of leukemic monocyte infiltration of the pulmonary interstitial spaces. In CMML with marked monocytosis, respiratory failure may be one of the important causes of death in addition to infection and bleeding.
我们报告了一例69岁慢性粒单核细胞白血病（CMML）患者，该患者并发致命性呼吸衰竭。胸部X线片显示双侧肺部浸润，并随白细胞计数增加而恶化。尸检证实肺间质存在白血病单核细胞浸润。在单核细胞显著增多的CMML中，呼吸衰竭可能是除感染和出血之外的重要死亡原因之一。
