Zhao Gui-Ling, Shi Min
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai, 200032, China.
Org Biomol Chem. 2005 Oct 21;3(20):3686-94. doi: 10.1039/b510572b. Epub 2005 Sep 9.
The attempted Baylis-Hillman reactions of N-tosyl aldimines and aryl aldehydes with 3-methylpenta-3,4-dien-2-one gave the corresponding Baylis-Hillman adducts 3 and 6 in moderate to good yields in the presence of DMAP in DMSO, respectively. In the case of the aza-Baylis-Hillman reactions of N-tosyl aldimines with 3-methylpenta-3,4-dien-2-one catalyzed by PBu3, the corresponding aza-Baylis-Hillman derivatives 4 and 5 were formed at the same time.
在二甲基亚砜中，N-对甲苯磺酰基醛亚胺和芳醛与3-甲基-3,4-戊二烯-2-酮尝试进行的贝利斯-希尔曼反应，分别在4-二甲氨基吡啶存在下以中等至良好的产率得到了相应的贝利斯-希尔曼加成物3和6。在三丁基膦催化的N-对甲苯磺酰基醛亚胺与3-甲基-3,4-戊二烯-2-酮的氮杂贝利斯-希尔曼反应中，同时形成了相应的氮杂贝利斯-希尔曼衍生物4和5。
