Li Xinyi, Zhang Wei, Chen Dongyan, Lin Yushuang, Huang Xiangwei, Shi Deli, Zhang Hongwei
Department of Biology, Shandong University, 27 Shanda nan road, Shandong, Jinan, 250100, People's Republic of China.
Dev Genes Evol. 2006 Jan;216(1):52-5. doi: 10.1007/s00427-005-0027-6. Epub 2005 Oct 7.
A novel gene, AmphiSom, was identified in amphioxus Branchiostoma belcheri tsingtauense. Its sequence and developmental expression pattern were determined. AmphiSom transcripts were first detected in the presomitic mesoderm at the late gastrula stage and reached the highest level in the forming and nascent somites in neurulae. However, the expression of AmphiSom was rapidly down-regulated after somites were formed. It was maintained in the most anterior somite and most posterior somite at neurula stages. By 48 h, AmphiSom transcripts were detected only in the developing tail bud but were no longer detected in 72-h larva. Our data demonstrated that the AmphiSom gene is expressed during the development of somites in amphioxus and could play a role in somite formation.
在青岛文昌鱼（Branchiostoma belcheri tsingtauense）中鉴定出一个新基因AmphiSom。确定了其序列和发育表达模式。AmphiSom转录本最早在原肠胚晚期的前体节中胚层中被检测到，并在神经胚形成和新生体节中达到最高水平。然而，体节形成后AmphiSom的表达迅速下调。在神经胚阶段，它在最前端和最后端的体节中持续表达。到48小时时，仅在发育中的尾芽中检测到AmphiSom转录本，而在72小时的幼虫中不再检测到。我们的数据表明，AmphiSom基因在文昌鱼体节发育过程中表达，并可能在体节形成中发挥作用。
