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柔脑膜转移瘤的当前治疗方法:全身化疗、鞘内化疗及症状管理。

Current treatment of leptomeningeal metastases: systemic chemotherapy, intrathecal chemotherapy and symptom management.

作者信息

Berg Stacey L, Chamberlain Marc C

机构信息

Norris Cancer Center, University of Southern California, Los Angeles, Ca. 90089, USA.

出版信息

Cancer Treat Res. 2005;125:121-46. doi: 10.1007/0-387-24199-x_8.

Abstract

Treatment of leptomeningeal metastases is multifaceted and includes symptomatic therapy, intrathecal and systemic chemotherapy, and radiotherapy. As the majority of patients have widespread incurable systemic tumor, treatment is predominantly palliative; however, some patients with leukemia, lymphoma or breast cancer may have prolonged remissions and the possibility of cure.

摘要

柔脑膜转移的治疗是多方面的,包括对症治疗、鞘内和全身化疗以及放疗。由于大多数患者存在广泛的无法治愈的全身肿瘤,治疗主要是姑息性的;然而,一些白血病、淋巴瘤或乳腺癌患者可能有较长的缓解期并有治愈的可能。

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