Berg Stacey L, Chamberlain Marc C
Norris Cancer Center, University of Southern California, Los Angeles, Ca. 90089, USA.
Cancer Treat Res. 2005;125:121-46. doi: 10.1007/0-387-24199-x_8.
Treatment of leptomeningeal metastases is multifaceted and includes symptomatic therapy, intrathecal and systemic chemotherapy, and radiotherapy. As the majority of patients have widespread incurable systemic tumor, treatment is predominantly palliative; however, some patients with leukemia, lymphoma or breast cancer may have prolonged remissions and the possibility of cure.
柔脑膜转移的治疗是多方面的,包括对症治疗、鞘内和全身化疗以及放疗。由于大多数患者存在广泛的无法治愈的全身肿瘤,治疗主要是姑息性的;然而,一些白血病、淋巴瘤或乳腺癌患者可能有较长的缓解期并有治愈的可能。