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[Effect of gene db dose on the development of beta-cytotropic and immunotropic effects of long-term glibenclamide administration in C57BL/KsJY mice].

作者信息

Gladkikh A I, Poltorak V V, Brindak O I, Blokh K O, Berestovskaia E V, Koshel' S P

出版信息

Tsitol Genet. 1992 Jan-Feb;26(1):20-6.

PMID:1621282
Abstract

The studies have revealed a modifying influence of gene db on the expressivity of damaging beta-cytotropic effect of long-term sulphanilamide therapy and on the development of autoimmune cell response to antigens of pancreatic islets. It is substantiated as promising to study a significance of individual genes and their doses in determining the variations of reactivity to beta-cytotropic and immunotropic effects of the chemical nature factors.

摘要

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