Emiroglu R, Moray G, Sevmis S, Sözen M H, Bilgin N, Haberal M
Baskent University Faculty of Medicine, Department of General Surgery, Ankara, Turkey.
Transplant Proc. 2005 Sep;37(7):2951-3. doi: 10.1016/j.transproceed.2005.08.044.
Kidney transplantation is considered the treatment of choice for children with end-stage renal disease (ESRD). From November 1975 to June 2004, 80 of a total of 1477 kidney transplantations were performed in 78 pediatric patients. We retrospectively reviewed the records of 42 boys and 36 girls. Patient age ranged from 8 to 16 years (mean, 14.9 +/- 2.2). Sixty-three (78.7) grafts were from living donors and 17 (21.3%) from deceased donors. Two patients (2.6%) underwent preemptive transplantation, while 76 had preoperative renal replacement therapy with either hemodialysis in 62 (79.5%) or peritoneal dialysis in 14 (17.9%). Although the cause of ESRD could not be established in 30 cases, the other 48 showed the most common etiologies to be reflux nephropathy and glomerulonephritis. In conclusion, despite relatively poor socioeconomic conditions and health care problems in our country, the overall outcomes for pediatric patients at our transplantation center are good. We seek to perform more preemptive kidney transplantations in children with ESRD, and to increase our efforts to educate the Turkish public about organ transplantation and donation.
肾移植被认为是终末期肾病(ESRD)患儿的首选治疗方法。1975年11月至2004年6月,在78例儿科患者中总共进行了1477例肾移植手术,其中80例。我们回顾性分析了42例男孩和36例女孩的记录。患者年龄在8至16岁之间(平均14.9 +/- 2.2岁)。63例(78.7%)移植物来自活体供体,17例(21.3%)来自已故供体。2例患者(2.6%)接受了抢先移植,而76例患者术前接受了肾脏替代治疗,其中62例(79.5%)进行了血液透析,14例(17.9%)进行了腹膜透析。虽然30例患者的ESRD病因无法确定,但其他48例显示最常见的病因是反流性肾病和肾小球肾炎。总之,尽管我国社会经济条件相对较差且存在医疗保健问题,但我们移植中心儿科患者的总体预后良好。我们寻求为ESRD患儿进行更多的抢先肾移植,并加大力度向土耳其公众宣传器官移植和捐赠。