Hefler Lukas A, Grimm Christoph, van Trotsenburg Michael, Nagele Friedrich
Division of Gynecologic Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.
Fertil Steril. 2005 Oct;84(4):1033-6. doi: 10.1016/j.fertnstert.2005.04.059.
In the present nonrandomized pilot study we determined the role of the vaginally administered aromatase inhibitor anastrozole (0.25 mg anastrozole/d for 6 months) in the treatment of women with histologically proven rectovaginal endometriosis. In a series of 10 patients, dysmenorrhea, physical and social functioning, but not chronic pelvic pain and dyspareunia, improved during therapy.
在本项非随机先导研究中，我们确定了经阴道给予芳香化酶抑制剂阿那曲唑（0.25毫克阿那曲唑/天，持续6个月）在治疗经组织学证实的直肠阴道子宫内膜异位症女性中的作用。在一组10例患者中，治疗期间痛经、身体和社会功能得到改善，但慢性盆腔疼痛和性交困难未得到改善。
