Tibayrenc Michel
UMR CNRS/IRD 2724, IRD, BP 64501, 34394 Montpellier cedex 5, France.
Trends Microbiol. 2005 Dec;13(12):575-80. doi: 10.1016/j.tim.2005.09.004. Epub 2005 Oct 7.
Molecular epidemiology designates the various molecular methods that aim to identify the relevant units of analysis of pathogens involved in transmissible diseases: species, subspecies, strains, clones and genes of interest. It is frequently based on an empirical approach. I advocate that evolutionary concepts enrich this discipline considerably and should be considered as an integral part. In turn, the experience and questioning of field experts are crucial to evolutionists who use transmissible diseases as models. A molecular epidemiology aim gives evolutionary studies a practical goal, putting a stop to approaches that are overly speculative.
感兴趣的物种、亚种、菌株、克隆和基因。它通常基于经验方法。我主张进化概念能极大地丰富这一学科,应被视为其不可或缺的一部分。反过来,领域专家的经验和质疑对将传染病用作模型的进化论者至关重要。分子流行病学目标为进化研究提供了一个实际目标,制止了过于投机的方法。