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Onset of inflammatory bowel diseases during combined alpha-interferon and ribavirin therapy for chronic hepatitis C: report of two cases.

作者信息

Villa Federica, Rumi Maria Grazia, Signorelli Clementina, Saibeni Simone, Del Ninno Ersilio, Ferrero Bogetto Stefano, de Franchis Roberto, Vecchi Maurizio

机构信息

Department of Gastroenterology, IRCCS Policlinico Hospital, Mangiagalli and Regina Elena Foundation, University of Milan, Italy.

出版信息

Eur J Gastroenterol Hepatol. 2005 Nov;17(11):1243-5. doi: 10.1097/00042737-200511000-00015.

DOI:10.1097/00042737-200511000-00015
PMID:16215439
Abstract

We report two patients who developed an inflammatory bowel disease (IBD) shortly after beginning combined alpha-interferon and ribavirin treatment for HCV-related chronic hepatitis. The previous clinical history was negative for IBD in both patients, who developed diarrhoea and rectal bleeding 10 days and 6 months, respectively, after the initiation of therapy. The history, therapeutic management and the possible causal relationships of these cases are discussed.

摘要

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