Barnea Anat, Mishal Adina, Nottebohm Fernando
Department of Natural and Life Sciences, The Open University of Israel, 108 Ravotsky St., P.O. Box 808, Ra'anana 43107, Israel.
Behav Brain Res. 2006 Feb 15;167(1):63-74. doi: 10.1016/j.bbr.2005.08.018. Epub 2005 Oct 10.
Male zebra finches reared in family groups were housed initially in small indoors cages with three other companions. At 4-5 months of age these birds were treated with [(3)H]-thymidine and then placed in large outdoors aviaries by themselves or with other zebra finches. Counts of new neurons were made 40, 60 and 150 days after the change in housing. Recruitment of new neurons in nidopallium caudale (NC) was higher than in the hippocampal complex (HC); but in both brain regions it was higher in communally housed birds than in birds housed singly, suggesting that the complexity of the social setting affects new neuron survival. In addition, the new neurons lived longer in rostral NC than in its caudal counterpart, and neuronal turnover was faster and more significant in NC than in HC. Albeit indirect, this may be the first suggestion that different parts of the brain upgrade memories at different time intervals, yielding an anatomical representation of time.
在家庭环境中饲养的雄性斑胸草雀最初被安置在小的室内笼子里，与另外三只同伴一起。在4 - 5个月大时，这些鸟接受了[³H] - 胸腺嘧啶核苷处理，然后单独或与其他斑胸草雀一起被安置在大型室外鸟舍中。在更换饲养环境后的40天、60天和150天对新神经元进行计数。尾侧巢皮质（NC）中新神经元的补充高于海马复合体（HC）；但在这两个脑区，群居鸟类中的新神经元补充都高于单独饲养的鸟类，这表明社会环境的复杂性会影响新神经元的存活。此外，新神经元在嘴侧NC中的存活时间比在尾侧NC中更长，并且NC中的神经元更新比HC更快且更显著。尽管是间接的，但这可能是第一个表明大脑不同部位在不同时间间隔更新记忆的迹象，从而产生时间的解剖学表征。
