Savoy Robert L
The Athinoula A. Martinos Center for Biomedical Imaging of the Massachusetts General Hospital, Harvard Medical School, HyperVision, Inc., US PO. Box number 158, Lexington, MA 02420, USA.
Brain Res Bull. 2005 Nov 15;67(5):361-7. doi: 10.1016/j.brainresbull.2005.06.008. Epub 2005 Jul 5.
The use of functional magnetic resonance imaging (fMRI) in cognitive neuroscience has expanded at an amazing rate in the past 10 years. Current research includes increasingly subtle and specific attempts to dissect the cognitive and emotional mechanisms called into play when humans make decisions. The present essay will briefly review some of the general considerations and domains of information needed when one designs fMRI-based experiments. However, the main theme will be the difficulties associated with designing, conducting, analyzing and interpreting such research. Functional MRI is an unusually complicated technique, and there are numerous ways for experiments to go wrong. As well as demanding exceptional care in maintaining the quality of one's own research, this makes the universal problem of evaluating other peoples' research particularly challenging.
在过去十年中，功能磁共振成像（fMRI）在认知神经科学中的应用以惊人的速度扩展。当前的研究包括越来越微妙和具体的尝试，以剖析人类做出决策时所涉及的认知和情感机制。本文将简要回顾在设计基于fMRI的实验时所需考虑的一些一般因素和信息领域。然而，主要主题将是与设计、进行、分析和解释此类研究相关的困难。功能磁共振成像是一种异常复杂的技术，实验出错的方式有很多。这不仅要求在保持自身研究质量方面格外小心，也使得评估他人研究这一普遍问题变得特别具有挑战性。
