Avendano M, Kunst A E, Huisman M, Lenthe F V, Bopp M, Regidor E, Glickman M, Costa G, Spadea T, Deboosere P, Borrell C, Valkonen T, Gisser R, Borgan J-K, Gadeyne S, Mackenbach J P
Department of Public Health, Erasmus Medical Centre, Rotterdam,The Netherlands.
Heart. 2006 Apr;92(4):461-7. doi: 10.1136/hrt.2005.065532. Epub 2005 Oct 10.
To assess the association between socioeconomic status and ischaemic heart disease (IHD) mortality in 10 western European populations during the 1990s.
Longitudinal study.
10 European populations (95,009,822 person years).
Longitudinal data on IHD mortality by educational level were obtained from registries in Finland, Norway, Denmark, England/Wales, Belgium, Switzerland, Austria, Turin (Italy), Barcelona (Spain), and Madrid (Spain). Age standardised rates and rate ratios (RRs) of IHD mortality by educational level were calculated by using Poisson regression.
IHD mortality was higher in those with a lower socioeconomic status than in those with a higher socioeconomic status among men aged 30-59 (RR 1.55, 95% confidence interval (CI) 1.51 to 1.60) and 60 years and over (RR 1.22, 95% CI 1.21 to 1.24), and among women aged 30-59 (RR 2.13, 95% CI 1.98 to 2.29) and 60 years and over (RR 1.36, 95% CI 1.33 to 1.38). Socioeconomic disparities in IHD mortality were larger in the Scandinavian countries and England/Wales, of moderate size in Belgium, Switzerland, and Austria, and smaller in southern European populations among men and younger women (p < 0.0001). For elderly women the north-south gradient was smaller and there was less variation between populations. No socioeconomic disparities in IHD mortality existed among elderly men in southern Europe.
Socioeconomic disparities in IHD mortality were larger in northern than in southern European populations during the 1990s. This partly reflects the pattern of socioeconomic disparities in cardiovascular risk factors in Europe. Population wide strategies to reduce risk factor prevalence combined with interventions targeted at the lower socioeconomic groups can contribute to reduce IHD mortality in Europe.
评估20世纪90年代10个西欧人群的社会经济地位与缺血性心脏病(IHD)死亡率之间的关联。
纵向研究。
10个欧洲人群(95,009,822人年)。
通过教育水平获取IHD死亡率的纵向数据,这些数据来自芬兰、挪威、丹麦、英格兰/威尔士、比利时、瑞士、奥地利、意大利都灵、西班牙巴塞罗那和西班牙马德里的登记处。使用泊松回归计算按教育水平划分的IHD死亡率的年龄标准化率和率比(RRs)。
在30 - 59岁男性中,社会经济地位较低者的IHD死亡率高于社会经济地位较高者(RR 1.55,95%置信区间(CI)1.51至1.60),60岁及以上男性中也是如此(RR 1.22,95% CI 1.21至1.24);在30 - 59岁女性中同样如此(RR 2.13,95% CI 1.98至2.29),60岁及以上女性中也是如此(RR 1.36,95% CI 1.33至1.38)。在斯堪的纳维亚国家和英格兰/威尔士,IHD死亡率的社会经济差异较大;在比利时、瑞士和奥地利,差异中等;在南欧人群中,男性和年轻女性的差异较小(p < 0.0001)。对于老年女性,南北梯度较小,人群之间的差异也较小。南欧老年男性中不存在IHD死亡率的社会经济差异。
20世纪90年代,北欧人群中IHD死亡率的社会经济差异大于南欧人群。这部分反映了欧洲心血管危险因素的社会经济差异模式。全人群降低危险因素患病率的策略,结合针对社会经济地位较低群体的干预措施,有助于降低欧洲的IHD死亡率。