Medical Information Center, Kyushu University Hospital, Fukuoka, Japan.
Department of Cardiovascular Medicine, Kyushu University, Fukuoka, Japan.
Epidemiol Health. 2022;44:e2022059. doi: 10.4178/epih.e2022059. Epub 2022 Jul 14.
Geographical variation in the standardized mortality ratio (SMR) for ischemic heart disease (IHD) among municipalities has not been assessed in Japan. Additionally, associations between area-level socioeconomic deprivation indices and IHD mortality have not been identified in Japan. The present study investigated this association.
Information on IHD mortality was extracted from Vital Statistics data from 2018 to 2020 for each municipality in Japan. The socioeconomic deprivation level was derived from multiple socioeconomic characteristics. We classified municipalities into quintiles based on the deprivation level and investigated the association between the deprivation level and the SMR of IHD. Additionally, a Bayesian spatial regression model was used to investigate this association, adjusting for other municipal characteristics.
Geographical variation in the SMR of IHD was revealed, and municipalities with high SMRs were spatially clustered. There was a weak negative correlation between the socioeconomic deprivation level and the SMRs (correlation coefficient, -0.057 for men and -0.091 for women). In contrast, the regression analysis showed a statistically significant positive association between deprived areas and the IHD mortality rate, and the relative risks for the most deprived municipalities compared with the least deprived municipalities were 1.184 (95% credible interval [CrI], 1.110 to 1.277) and 1.138 (95% CrI, 1.048 to 1.249) for men and women, respectively.
A weak negative correlation between the socioeconomic deprivation level and the SMR was observed in the descriptive analysis, while the regression analysis showed that living in deprived areas was statistically positively associated with the IHD mortality rate.
在日本,尚未评估各市区缺血性心脏病(IHD)标准化死亡率(SMR)的地理差异。此外,在日本,也尚未确定区域社会经济剥夺指数与 IHD 死亡率之间的关联。本研究调查了这种关联。
从日本 2018 年至 2020 年的生命统计数据中提取 IHD 死亡率信息。社会经济剥夺程度来自多个社会经济特征。我们根据剥夺程度将市区分为五组,并调查剥夺程度与 IHD 的 SMR 之间的关联。此外,还使用贝叶斯空间回归模型调整其他市区特征后对该关联进行了调查。
揭示了 IHD 的 SMR 的地理差异,并且具有高 SMR 的市区呈空间聚集。社会经济剥夺程度与 SMR 之间存在微弱的负相关(男性的相关系数为-0.057,女性为-0.091)。相反,回归分析显示,贫困地区与 IHD 死亡率之间存在统计学上显著的正相关,与最贫困的市区相比,最贫困的市区的相对风险分别为 1.184(95%可信区间[CrI],1.110 至 1.277)和 1.138(95%CrI,1.048 至 1.249),男性和女性分别如此。
在描述性分析中观察到社会经济剥夺程度与 SMR 之间存在微弱的负相关,而回归分析表明,生活在贫困地区与 IHD 死亡率呈统计学上的正相关。