A multifunctional enzyme adds to its repertoire.
作者信息
Walseth Timothy F
机构信息
Department of Pharmacology, University of Minnesota Medical School, 6-120 Jackson Hall, 321 Church Street Southeast, Minneapolis, MN 55455, USA.
出版信息
Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):14941-2. doi: 10.1073/pnas.0507258102. Epub 2005 Oct 10.
Abstract
摘要
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本文引用的文献
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ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells.ADP-核糖基环化酶可生成两种对哺乳动物细胞具有细胞毒性活性的特殊腺嘌呤同型二核苷酸。
Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14509-14. doi: 10.1073/pnas.0503691102. Epub 2005 Sep 19.
2
Structure and enzymology of ADP-ribosyl cyclases: conserved enzymes that produce multiple calcium mobilizing metabolites.ADP-核糖基环化酶的结构与酶学：产生多种钙动员代谢产物的保守酶类
Curr Mol Med. 2004 May;4(3):249-61. doi: 10.2174/1566524043360708.
3
Multiplicity of Ca2+ messengers and Ca2+ stores: a perspective from cyclic ADP-ribose and NAADP.钙离子信使与钙离子储存的多样性：从环二磷酸腺苷核糖和烟酰胺腺嘌呤二核苷酸磷酸的角度来看
Curr Mol Med. 2004 May;4(3):227-37. doi: 10.2174/1566524043360753.
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Evidence for an intracellular ADP-ribosyl cyclase/NAD+-glycohydrolase in brain from CD38-deficient mice.来自CD38基因敲除小鼠大脑中细胞内ADP-核糖基环化酶/NAD+糖水解酶的证据。
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ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.Nudix基序同源性揭示钙通透性LTRPC2通道的ADP核糖门控
Nature. 2001 May 31;411(6837):595-9. doi: 10.1038/35079100.
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Physiological functions of cyclic ADP-ribose and NAADP as calcium messengers.环磷酸腺苷核糖（cADPR）和烟酰胺腺嘌呤二核苷酸磷酸（NAADP）作为钙信使的生理功能。
Annu Rev Pharmacol Toxicol. 2001;41:317-45. doi: 10.1146/annurev.pharmtox.41.1.317.
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Dinucleotides as growth-promoting extracellular mediators. Presence of dinucleoside diphosphates Ap2A, Ap2G, and Gp2G in releasable granules of platelets.二核苷酸作为促进生长的细胞外介质。血小板可释放颗粒中存在二核苷二磷酸Ap2A、Ap2G和Gp2G。
J Biol Chem. 2001 Mar 23;276(12):8904-9. doi: 10.1074/jbc.M009527200. Epub 2000 Dec 13.
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Dinucleoside polyphosphates-friend or foe?二核苷多磷酸——是友还是敌？
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