Phillips Barbara, Mannino David M
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY, USA.
Sleep. 2005 Aug 1;28(8):965-71. doi: 10.1093/sleep/28.8.965.
We investigated the prevalence and hazard ratios for insomnia complaints in a large cohort of middle-aged men and women.
The Atherosclerosis Risk in Communities Study is a prospective study of cardiovascular disease. Using multivariate regression analysis, we predicted the likelihood of endorsing the insomnia complaints by age, sex, alcohol intake, smoking, diabetes, heart disease, menopausal status, use of hypnotics, hypertension, depressive symptoms, education level, body mass index, respiratory symptoms, and pulmonary function status. We predicted the hazard ratios (HR) of death at 6.3 +/- 1.1 year by endorsement of insomnia complaints and by hypnotic use controlling for covariates.
North American communities.
13563 participants aged 45 to 69 years at baseline
None.
The prevalence of insomnia complaints in this cohort was 23%. Predictors of insomnia complaints were female sex (odds ratio [OR] 0.56, 95% confidence interval [CI] 0.45-0.70 for men), annual family income below 50,000 dollars (OR 1.23, CI 1.09-1.40), age 40 to 49 years (OR 1.29, CI 1.11-1.50), depressive symptoms (OR 5.05, CI 4.60-5.55), heart disease (OR 1.89, CI 1.67-2.14), severe airflow obstruction (OR 1.61, CI 1.17-2.22), pulmonary symptoms (OR 1.71, CI 1.5-1.95), and restrictive lung disease (OR 1.27, CI 1.10-1.47). After controlling for covariates, insomnia complaints were not associated with an increased risk for death (OR 1.01, CI 0.85-1.21), nor was the use of hypnotics (OR 1.38, CI 0.90-2.13).
In this cohort, the prevalence of insomnia complaints was 23%. After controlling for confounders, neither insomnia complaints nor hypnotic use predicted increased mortality over 6.3 years.
我们调查了一大群中年男性和女性中失眠主诉的患病率及风险比。
社区动脉粥样硬化风险研究是一项关于心血管疾病的前瞻性研究。我们使用多变量回归分析，根据年龄、性别、酒精摄入量、吸烟情况、糖尿病、心脏病、绝经状态、催眠药使用情况、高血压、抑郁症状、教育水平、体重指数、呼吸道症状和肺功能状态，预测出现失眠主诉的可能性。我们通过失眠主诉及催眠药使用情况并控制协变量，预测了6.3±1.1年时的死亡风险比（HR）。
北美社区。
13563名基线年龄在45至69岁的参与者
无。
该队列中失眠主诉的患病率为23%。失眠主诉的预测因素包括女性（男性的比值比[OR]为0.56，95%置信区间[CI]为0.45 - 0.70）、家庭年收入低于50000美元（OR 1.23，CI 1.09 - 1.40）、年龄40至49岁（OR 1.29，CI 1.11 - 1.50）、抑郁症状（OR 5.05，CI 4.60 - 5.55）、心脏病（OR 1.89，CI 1.67 - 2.14）、严重气流阻塞（OR 1.61，CI 1.17 - 2.22）、肺部症状（OR 1.71，CI 1.5 - 1.95）和限制性肺病（OR 1.27，CI 1.10 - 1.47）。在控制协变量后，失眠主诉与死亡风险增加无关（OR 1.01，CI 0.85 - 1.21），催眠药的使用情况也与死亡风险增加无关（OR 1.38，CI 0.90 - 2.13）。
在该队列中，失眠主诉的患病率为23%。在控制混杂因素后，失眠主诉和催眠药的使用在6.3年期间均未预测死亡率增加。
