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癌症相关性失眠的发病机制与管理

Pathogenesis and management of cancer-related insomnia.

作者信息

Graci Gina

机构信息

Northwestern University, Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois 60611, USA.

出版信息

J Support Oncol. 2005 Sep-Oct;3(5):349-59.

PMID:16218258
Abstract

Insomnia is the most common sleep disorder reported by cancer patients. Oncologists have noticed that alterations in sleep patterns are endemic among their patients, yet sleep problems are rarely assessed in a typical patient evaluation. Other concerns, such as morbidity and mortality, appear to take precedence. The cause of chronic sleep difficulties is multifaceted and up until recently, little attention has been given to the potential factors associated with the pathogenesis of cancer-related insomnia. The unique contributions of psychologic, medical, treatment side effects, environmental, behavioral, and pharmaceutical pathways on cancer-related insomnia cannot be ignored. This paper explores an overview of the incidence and severity of sleep disturbance in cancer patients, a review of the mechanisms of sleep, and the potential factors associated with the pathogenesis of cancer-related insomnia. Nurses, physicians, and other healthcare providers are in a unique position to greatly improve the quality of sleep in cancer patients. Cancer patients face many challenges; sleep problems do not have to be one of the necessary consequences associated with the cancer experience.

摘要

失眠是癌症患者报告的最常见睡眠障碍。肿瘤学家已经注意到睡眠模式改变在他们的患者中很普遍,但在典型的患者评估中很少评估睡眠问题。其他问题,如发病率和死亡率,似乎更为优先。慢性睡眠困难的原因是多方面的,直到最近,与癌症相关失眠发病机制相关的潜在因素很少受到关注。心理、医学、治疗副作用、环境、行为和药物途径对癌症相关失眠的独特影响不容忽视。本文探讨了癌症患者睡眠障碍的发生率和严重程度概述、睡眠机制综述以及与癌症相关失眠发病机制相关的潜在因素。护士、医生和其他医疗保健提供者处于独特的地位,可以极大地改善癌症患者的睡眠质量。癌症患者面临许多挑战;睡眠问题不一定是与癌症经历相关的必然结果之一。

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