Kusiak A, Sadlak-Nowicka J, Limon J, Kochańska B
Department of Conservative Dentistry, Medical University of Gdansk, Gdansk, Poland.
Int Endod J. 2005 Nov;38(11):822-6. doi: 10.1111/j.1365-2591.2005.01023.x.
To analyse root morphology of mandibular premolars in 40 females with Turner syndrome.
All patients aged 18-50 years (mean+/-SD: 26.2+/-6.22) were clinically and cytogenetically diagnosed and divided into three groups according to karyotype: I-with 45,X (n=19); II-with 46,X,i(Xq) and other structural changes of this chromosome (n=8); III-with mos45,X/46,XX and other mosaic karyotype (n=13). The control group consisted of 30 healthy women aged 20-50 years (mean+/-SD: 31.52+/-5.21) who underwent dental treatment at the Department of Conservative Dentistry and Department of Periodontology and Oral Mucosa Diseases, Medical University of Gdańsk, Poland. The root morphology of mandibular premolars was studied based on orthopantomogram X-ray images. The results were analysed using chi-square test with Yates's adjustment.
Separate mesial and distal root canals and separate root apices were noted on orthopantomograms in patients with Turner syndrome. Two-rooted mandibular first premolars were observed in 34% of cases in group 45,X (group I), in 31% of cases in the group with structural aberrations of chromosome X (group II) and in 31% of cases with mosaic karyotypes (group III). Two-rooted mandibular second premolars were observed in 39% cases in group 45,X and in 31% of cases in the group with structural aberrations of chromosome X and in 35% of cases with mosaic karyotypes. This type of root morphology was not observed in the control group. No significant difference was found between the three groups of Turner syndrome.
Highly significant differences in root morphology of mandibular premolars between patients with Turner syndrome and a population control group were found.
分析40例特纳综合征女性患者下颌前磨牙的牙根形态。
所有年龄在18 - 50岁（平均±标准差：26.2±6.22）的患者均经过临床和细胞遗传学诊断，并根据核型分为三组：I组 - 45,X（n = 19）；II组 - 46,X,i(Xq)及该染色体的其他结构改变（n = 8）；III组 - mos45,X/46,XX及其他嵌合核型（n = 13）。对照组由30名年龄在20 - 50岁（平均±标准差：31.52±5.21）的健康女性组成，她们在波兰格但斯克医科大学保守牙科、牙周病与口腔黏膜病科接受牙科治疗。基于曲面体层X线影像研究下颌前磨牙的牙根形态。采用Yates校正的卡方检验分析结果。
在特纳综合征患者的曲面体层片上观察到近中根管和远中根管分开以及根尖分开的情况。在45,X组（I组）中，34%的病例观察到双根下颌第一前磨牙；在X染色体结构异常组（II组）中，31%的病例观察到双根下颌第一前磨牙；在嵌合核型组（III组）中，31%的病例观察到双根下颌第一前磨牙。在45,X组中，39%的病例观察到双根下颌第二前磨牙；在X染色体结构异常组中，31% 的病例观察到双根下颌第二前磨牙；在嵌合核型组中，35%的病例观察到双根下颌第二前磨牙。对照组未观察到这种牙根形态。特纳综合征的三组之间未发现显著差异。
发现特纳综合征患者与人群对照组在下颌前磨牙牙根形态上存在高度显著差异。
