坦桑尼亚西北部孕期曼氏血吸虫感染及其与贫血的关联

Schistosoma mansoni in pregnancy and associations with anaemia in northwest Tanzania.

作者信息

Ajanga Antony, Lwambo Nicholas J S, Blair Lynsey, Nyandindi Ursuline, Fenwick Alan, Brooker Simon

机构信息

Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

出版信息

Trans R Soc Trop Med Hyg. 2006 Jan;100(1):59-63. doi: 10.1016/j.trstmh.2005.06.024. Epub 2005 Oct 10.

DOI:10.1016/j.trstmh.2005.06.024

PMID:16219330

Abstract

Schistosomiasis among pregnant women has been inadequately investigated. In order to determine the importance of Schistosoma mansoni in this subgroup, we conducted a cross-sectional survey of 972 women in Tanzania and investigated the prevalence of Schistosoma mansoni, hookworm and malaria and their associations with anaemia. Overall, 63.5% of women were infected with S. mansoni, with prevalence highest among younger women and decreasing with increasing age. The prevalence of hookworm was 56.3%, and 16.4% of women had malaria parasitaemia. Overall, 66.4% of women were anaemic. Increased risk of anaemia was associated with heavy infection with S. mansoni but not hookworm or Plasmodium falciparum parasitaemia.

摘要

孕妇血吸虫病的调查尚不充分。为了确定曼氏血吸虫在这一亚组人群中的重要性，我们在坦桑尼亚对972名妇女进行了横断面调查，研究了曼氏血吸虫、钩虫和疟疾的流行情况及其与贫血的关联。总体而言，63.5%的妇女感染了曼氏血吸虫，感染率在年轻女性中最高，并随年龄增长而下降。钩虫感染率为56.3%，16.4%的妇女有疟原虫血症。总体而言，66.4%的妇女贫血。贫血风险增加与曼氏血吸虫重度感染有关，但与钩虫或恶性疟原虫血症无关。