Cando Leslie Faye T, Perias Glenmarie Angelica S, Tantengco Ourlad Alzeus G, Dispo Micah D, Ceriales Jeremy A, Girasol Mark John G, Leonardo Lydia R, Tabios Ian Kim B
College of Medicine, University of the Philippines Manila, Manila 1000, Philippines.
Department of Epidemiology and Biostatistics, College of Public Health, University of the Philippines Manila, Manila 1000, Philippines.
Trop Med Infect Dis. 2022 Nov 4;7(11):354. doi: 10.3390/tropicalmed7110354.
Schistosomiasis is a neglected tropical disease affecting 40 million women of childbearing age worldwide. Its global disease prevalence among pregnant women is still unknown. This meta-analysis determined the pooled prevalence of schistosomiasis among pregnant women globally. Additionally, this study also determined the pooled prevalence based on infection intensity based on eggs per gram. Observational studies on the prevalence of schistosomiasis among pregnant patients were obtained from Medline, Scopus, and CINAHL from January 2001 until August 2020. A review of titles and abstracts was done independently by six reviewers. The quality of the included studies was assessed using the Newcastle-Ottawa Scale for case-control, cohort, and cross-sectional studies. A total of 27 studies were included in the meta-analysis and meta-regression. The pooled prevalence of was 13.44 (CI: 8.90-19.80) per 100 observations, while the pooled prevalence of was 12.18 (CI: 4.47-29.12) per 100 observations. The prevalence of infection in one study was 53.54 (CI: 43.23-63.62) per 100 observations. Our results showed a prevailing health problem of schistosomiasis during pregnancy in various countries worldwide. This strengthens the need to conduct more schistosomiasis research, prevention, and control programs in pregnant women.
血吸虫病是一种被忽视的热带病，全球有4000万育龄妇女受其影响。其在全球孕妇中的疾病流行率仍未知。这项荟萃分析确定了全球孕妇中血吸虫病的合并流行率。此外，本研究还根据每克虫卵数确定了基于感染强度的合并流行率。2001年1月至2020年8月期间，从医学期刊数据库（Medline）、Scopus数据库和护理学与健康领域数据库（CINAHL）获取了关于孕妇血吸虫病流行率的观察性研究。由六名评审员独立对标题和摘要进行审查。使用纽卡斯尔-渥太华量表对纳入研究的病例对照研究、队列研究和横断面研究的质量进行评估。共有27项研究纳入荟萃分析和荟萃回归。每100例观察对象中，[此处原文似乎有缺失内容]的合并流行率为13.44（95%置信区间：8.90 - 19.80），而每100例观察对象中，[此处原文似乎有缺失内容]的合并流行率为12.18（95%置信区间：4.47 - 29.12）。一项研究中，每100例观察对象的[此处原文似乎有缺失内容]感染率为53.54（95%置信区间：43.23 - 63.62）。我们的结果表明，全球各国孕期血吸虫病是一个普遍存在的健康问题。这强化了对孕妇开展更多血吸虫病研究、预防和控制项目的必要性。
