Lee Jennifer M, Davenport Guy F, Marshall David, Ellis T H Noel, Ambrose Michael J, Dicks Jo, van Hintum Theo J L, Flavell Andrew J
Department of Life Sciences, University of Dundee, Scotland, UK.
Plant Physiol. 2005 Oct;139(2):619-31. doi: 10.1104/pp.105.065201.
The extensive germplasm resource collections that are now available for major crop plants and their wild relatives will increasingly provide valuable biological and bioinformatics resources for plant physiologists and geneticists to dissect the molecular basis of key traits and to develop highly adapted plant material to sustain future breeding programs. A key to the efficient deployment of these resources is the development of information systems that will enable the collection and storage of biological information for these plant lines to be integrated with the molecular information that is now becoming available through the use of high-throughput genomics and post-genomics technologies. The GERMINATE database has been designed to hold a diverse variety of data types, ranging from molecular to phenotypic, and to allow querying between such data for any plant species. Data are stored in GERMINATE in a technology-independent manner, such that new technologies can be accommodated in the database as they emerge, without modification of the underlying schema. Users can access data in GERMINATE databases either via a lightweight Perl-CGI Web interface or by the more complex Genomic Diversity and Phenotype Connection software. GERMINATE is released under the GNU General Public License and is available at http://germinate.scri.sari.ac.uk/germinate/.
目前可获得的主要农作物及其野生近缘种的广泛种质资源库,将越来越多地为植物生理学家和遗传学家提供有价值的生物学和生物信息学资源,以剖析关键性状的分子基础,并培育高度适应环境的植物材料,以维持未来的育种计划。有效利用这些资源的关键在于开发信息系统,使这些植物品系的生物信息的收集和存储能够与目前通过高通量基因组学和后基因组学技术获得的分子信息整合起来。GERMINATE数据库旨在容纳从分子到表型的各种数据类型,并允许对任何植物物种的此类数据进行查询。数据以与技术无关的方式存储在GERMINATE中,这样随着新技术的出现,可以在不修改底层模式的情况下将其纳入数据库。用户可以通过轻量级的Perl-CGI网络界面或更复杂的基因组多样性与表型连接软件访问GERMINATE数据库中的数据。GERMINATE根据GNU通用公共许可证发布,可在http://germinate.scri.sari.ac.uk/germinate/获取。