抗癌药物研发与应用中的建模与模拟：一种未得到充分利用的工具？
Modelling and simulation in the development and use of anti-cancer agents: an underused tool?
作者信息
Rombout Ferdinand, Aarons Leon, Karlsson Mats, Man Anthony, Mentré France, Nygren Peter, Racine Amy, Schaefer Hans, Steimer Jean-Louis, Troconiz Iñaki, van Peer Achiel
机构信息
Department for Modelling and Simulation, Grünenthal GmbH, P.O. Box 500444, 52088 Aachen, Germany.
出版信息
J Pharmacokinet Pharmacodyn. 2004 Dec;31(6):419-40. doi: 10.1007/s10928-005-5910-2.
To help identify the role of modelling and simulation in the development of anti-cancer agents, their main advantages and the obstacles to their rational use, an expert meeting was organized by COST B15. This manuscript presents a synthesis of views expressed at that meeting and indicates future directions. The manuscript also shows some examples where modelling and simulation have proven to be of relevant value in the drug development process for anti-cancer agents.
为了明确建模与模拟在抗癌药物研发中的作用、其主要优势以及合理应用所面临的障碍，欧洲科学与技术合作组织（COST）的B15行动组组织了一次专家会议。本手稿总结了该会议上表达的观点，并指出了未来的发展方向。手稿还展示了一些建模与模拟在抗癌药物研发过程中已证明具有重要价值的实例。
Zotero 插件