Tanizaki Y, Kitani H, Okazaki M, Mifune T, Mitsunobu F, Kotoh N, Tada S, Takahashi K, Kimura I
Division of Medicine, Misasa Medical Branch, Okayama University Medical School.
Arerugi. 1992 Apr;41(4):489-96.
Asthma classification by clinical symptoms and signs (clinical diagnosis) was compared with the classification by score calculated from clinical findings and examinations (score diagnosis) in 25 patients with bronchial asthma. 1. Ten subjects classified as Ia (simple bronchoconstriction type) by clinical diagnosis were divided into 6 cases with expectoration of less than 49 ml a day and 4 cases with expectoration of between 50 and 99 ml. The level of serum IgE and number of eosinophils in BALF were significantly higher in the latter cases than in the former cases. The cases whose expectoration was from 50 to 99 ml a day were classified as Ib (bronchoconstriction with hypersecretion type) by score diagnosis. 2. The six subjects who were classified as type Ib by clinical diagnosis were also evaluated as type Ib by score diagnosis. 3. Nine of the 10 subjects classified as type II by clinical diagnosis were evaluated as type II by score diagnosis. One case, whose score was under 12 points, was evaluated as questionable type II by score diagnosis.
对25例支气管哮喘患者，比较了根据临床症状和体征进行的哮喘分类（临床诊断）与根据临床检查结果计算的评分进行的分类（评分诊断）。1. 临床诊断为Ia型（单纯支气管收缩型）的10名受试者，分为每日咳痰量少于49 ml的6例和咳痰量在50至99 ml之间的4例。后一组病例的血清IgE水平和支气管肺泡灌洗术（BALF）中的嗜酸性粒细胞数量显著高于前一组病例。根据评分诊断，每日咳痰量为50至99 ml的病例被归类为Ib型（伴有分泌亢进的支气管收缩型）。2. 临床诊断为Ib型的6名受试者，根据评分诊断也被评估为Ib型。3. 临床诊断为II型的10名受试者中，9名根据评分诊断被评估为II型。1例评分低于12分，根据评分诊断被评估为可疑II型。
