Nelissen Koen, Luppino Giuseppe, Vanduffel Wim, Rizzolatti Giacomo, Orban Guy A
Laboratorium voor Neuro-en Psychofysiologie, Katholieke Universiteit Leuven Medical School, Leuven, Belgium.
Science. 2005 Oct 14;310(5746):332-6. doi: 10.1126/science.1115593.
Observation of actions performed by others activates monkey ventral premotor cortex, where action meaning, but not object identity, is coded. In a functional MRI (fMRI) study, we investigated whether other monkey frontal areas respond to actions performed by others. Observation of a hand grasping objects activated four frontal areas: rostral F5 and areas 45B, 45A, and 46. Observation of an individual grasping an object also activated caudal F5, which indicates different degrees of action abstraction in F5. Observation of shapes activated area 45, but not premotor F5. Convergence of object and action information in area 45 may be important for full comprehension of actions.
观察他人执行的动作会激活猴子的腹侧运动前区皮层，该区域编码动作的意义而非物体的身份。在一项功能磁共振成像（fMRI）研究中，我们调查了猴子其他额叶区域是否对他人执行的动作做出反应。观察一只手抓取物体激活了四个额叶区域：吻侧F5以及45B区、45A区和46区。观察个体抓取物体也激活了尾侧F5，这表明F5区存在不同程度的动作抽象。观察形状激活了45区，但未激活运动前区F5。45区中物体和动作信息的汇聚对于全面理解动作可能很重要。
