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1型糖尿病患儿的总胆固醇和高密度脂蛋白水平

Total cholesterol and high-density lipoprotein levels in pediatric subjects with type 1 diabetes mellitus.

作者信息

Maahs David M, Maniatis Aristides K, Nadeau Kristen, Wadwa R Paul, McFann Kim, Klingensmith Georgeanna J

机构信息

Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA.

出版信息

J Pediatr. 2005 Oct;147(4):544-6. doi: 10.1016/j.jpeds.2005.04.068.

Abstract

This study reports serum lipid levels in 682 children with type 1 diabetes mellitus. We found that 3.5% of the subjects had a high-density lipoprotein (HDL) cholesterol level < 35 mg/dL, 15.4% had a total cholesterol (TC) level>200 mg/dL, and 18.6% were abnormal for either HDL or TC, compared with prevalences of 5.7%, 11.2%, and 16.3%, respectively, reported in the National Health and Nutrition Examination Survey 2001-02. Hemoglobin A1c value was significantly related to TC and non-HDL cholesterol levels.

摘要

本研究报告了682例1型糖尿病患儿的血脂水平。我们发现,3.5%的受试者高密度脂蛋白(HDL)胆固醇水平<35mg/dL,15.4%的受试者总胆固醇(TC)水平>200mg/dL,18.6%的受试者HDL或TC异常,而2001 - 2002年全国健康与营养检查调查报道的患病率分别为5.7%、11.2%和16.3%。糖化血红蛋白值与TC和非HDL胆固醇水平显著相关。

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