糖尿病儿童的非高密度脂蛋白胆固醇：基于血糖控制、体重指数、年龄、性别和公认切点的治疗建议
Non-High-Density Lipoprotein Cholesterol in Children with Diabetes: Proposed Treatment Recommendations Based on Glycemic Control, Body Mass Index, Age, Sex, and Generally Accepted Cut Points.
作者信息
Schwab K Otfried, Doerfer Jürgen, Hungele Andreas, Scheuing Nicole, Krebs Andreas, Dost Axel, Rohrer Tilman R, Hofer Sabine, Holl Reinhard W
机构信息
Department of Pediatrics and Adolescent Medicine, University Medical Center, Freiburg, Germany.
Department of Pediatrics and Adolescent Medicine, University Medical Center, Freiburg, Germany.
出版信息
J Pediatr. 2015 Dec;167(6):1436-9. doi: 10.1016/j.jpeds.2015.09.006. Epub 2015 Oct 1.
Percentile-based non-high-density lipoprotein cholesterol levels were analyzed by glycemic control, weight, age, and sex of children with type 1 diabetes (n = 26,358). Ten percent of all children and 25% of overweight adolescent girls require both immediate lipid-lowering medication and lifestyle changes to achieve non-high-density lipoprotein cholesterol levels <120 mg/dL and cardiovascular risk reduction.
基于百分位数的非高密度脂蛋白胆固醇水平，按1型糖尿病患儿（n = 26358）的血糖控制情况、体重、年龄和性别进行了分析。所有儿童中的10%以及25%的超重青春期女孩需要立即进行降脂药物治疗和生活方式改变，以实现非高密度脂蛋白胆固醇水平<120 mg/dL并降低心血管疾病风险。
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