Calli Cağlar, Oncel Semih, Pinar Ercan, Güçlü Elif, Calli Aylin, Apaydin Melda
Department of 3rd Otolaryngology, Izmir Atatürk Training Hospital, Izmir, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2005;14(1-2):35-8.
Castleman's disease is a rare disorder characterized by massive proliferation of the lymphoid tissue due to an unknown cause. Two clinical types (localized, multicentric) have been described with three histological variants (hyaline-vascular, plasma cell, and mixed type). A 47-year-old female patient was referred to our department because of a swelling in the posterior cervical region. Fine-needle aspiration biopsy was suggestive of lymphoma. Total excision of the mass was performed under general anesthesia with intraoperative frozen section examination. Histopathologic diagnosis was Castleman's disease of hyaline-vascular type. Castleman's disease should also be considered for suspicious masses in the neck.
卡斯特leman病是一种罕见疾病,其特征是由于不明原因导致淋巴组织大量增生。已描述了两种临床类型(局限性、多中心性)和三种组织学变体(透明血管型、浆细胞型和混合型)。一名47岁女性患者因颈后部肿胀被转诊至我科。细针穿刺活检提示为淋巴瘤。在全身麻醉下进行肿块全切,并进行术中冰冻切片检查。组织病理学诊断为透明血管型卡斯特leman病。对于颈部可疑肿块也应考虑卡斯特leman病。