Somdas Mehmet Akif, Ketenci Ibrahim, Bicer Sohbet, Senturk Mehmet, Guney Ercihan
Department of Otolaryngology-Head and Neck Surgery, Erciyes University Medical Faculty, Kayseri, Turkey.
Ann Otol Rhinol Laryngol. 2004 Jun;113(6):459-61. doi: 10.1177/000348940411300608.
Castleman's disease is a rare, benign disease of unknown cause that induces reactive lymph node hyperplasia, most commonly in the mediastinum. It has 2 histologic subtypes: hyaline vascular and plasma cellular. A definitive diagnosis necessitates tissue biopsy. A specimen may be even misdiagnosed as lymphoma in frozen section. Surgery is the treatment of choice for the solitary form, whereas chemotherapy, radiotherapy, and steroids are proposed for the multicentric type. A neck mass diagnosed as Castleman's disease in a 48-year-old woman is reported.
卡斯特leman病是一种病因不明的罕见良性疾病，可引起反应性淋巴结增生，最常见于纵隔。它有两种组织学亚型：透明血管型和浆细胞型。明确诊断需要组织活检。在冰冻切片中，标本甚至可能被误诊为淋巴瘤。手术是孤立型的首选治疗方法，而多中心型则建议采用化疗、放疗和使用类固醇。本文报道了一名48岁女性被诊断为卡斯特leman病的颈部肿块病例。
