Yamamoto Manabu, Mashino Koujiro, Shibahara Kotaro, Oki Eiji, Kakeji Yoshihiro, Baba Hideo, Maehara Yoshihiko
Dept. of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University.
Gan To Kagaku Ryoho. 2005 Oct;32(10):1389-92.
Peritoneal dissemination with advanced gastric cancer is of significant problem. Peritoneal lavage cytology has been an effective method for the detection of early peritoneal dissemination since 1999. The accurate evaluation of peritoneal lavage cytology is unclear except for the same prognosis of peritoneal dissemination. We examined the clinical findings and the prognosis with positive cases in peritoneal lavage cytology. The prognosis of cases with P1CY1 or P2P3 group was poorer than in the P0CY1 or P0, CY1 group. We thus review the evaluation of peritoneal lavage cytology with gastric cancer in the Japanese and English literature. In addition, we describe the diagnosis of early peritoneal dissemination using peritoneal lavage tumor markers or molecular markers of peritoneal lavage.
晚期胃癌的腹膜播散是一个重大问题。自1999年以来，腹腔灌洗细胞学一直是检测早期腹膜播散的有效方法。除了腹膜播散的相同预后外，腹腔灌洗细胞学的准确评估尚不清楚。我们研究了腹腔灌洗细胞学阳性病例的临床特征和预后。P1CY1或P2P3组病例的预后比P0CY1或P0、CY1组差。因此，我们回顾了日本和英文文献中关于胃癌腹腔灌洗细胞学的评估。此外，我们描述了使用腹腔灌洗肿瘤标志物或腹腔灌洗分子标志物诊断早期腹膜播散的方法。
