Ishihara Chihiro, Noguchi Yoshikazu, Yoshikawa Takaki, Ando Kouhei, Shotsu Masako, Ishiwa Naoki, Takeda Akira, Morinaga Soichiro, Yamamoto Yuji, Yoshida Sachiko, Ogoshi Takafumi
Dept. of Surgery, Yokohama City Kowan Hospital.
Gan To Kagaku Ryoho. 2005 Oct;32(10):1461-3.
We reported 2 cases with advanced gastric cancer, successfully treated with TS-1 and CDDP. Case 1 had Type 3 gastric cancer with left supra-clavicular (Virchow) and para-aortic lymph node metastases. Those distant node metastases completely disappeared after two courses of neoadjuvant chemotherapy (NAC) consisting of TS-1/ CDDP, and radical surgery for cure was conducted. The second case had Type 3 carcinoma with peritoneal dissemination. The primary lesion significantly decreased after four courses of the combination chemotherapy. The patient has been alive for 1 year and a half after 14 courses of TS-1/CDDP with stable disease. Significance of TS-1/CDDP in far advanced gastric cancer was discussed.
我们报告了2例晚期胃癌患者，经替吉奥（TS-1）和顺铂（CDDP）成功治疗。病例1为3型胃癌，伴有左锁骨上（魏尔啸）和主动脉旁淋巴结转移。经过由替吉奥/顺铂组成的两个疗程新辅助化疗（NAC）后，那些远处淋巴结转移完全消失，随后进行了根治性手术。第二例为伴有腹膜播散的3型癌。联合化疗四个疗程后，原发灶明显缩小。该患者在接受14个疗程替吉奥/顺铂治疗且病情稳定后已存活1年半。讨论了替吉奥/顺铂在晚期胃癌中的意义。
