Tsukahara Akihiro, Kaneko Kazuhiro, Tanaka Syuji
Dept. of Surgery, Niigata Prefectural Koide Hospital.
Gan To Kagaku Ryoho. 2004 Nov;31(12):2039-41.
A Case of Advanced Gastric Cancer with Multiple Liver Metastases Successfully Treated with TS-1 and CDDP: Akihiro Tsukahara, Kazuhiro Kaneko and Syuji Tanaka (Dept. of Surgery, Niigata Prefectural Koide Hospital) Summary A 70-year-old advanced gastric cancer patient with liver and lymph node metastases was treated by chemotherapy with TS-1 and CDDP. One course consisted of administration of TS-1 100 mg/body for 21 days followed by 14 days rest and infusion of CDDP 80 mg/body on day 8. At the end of 2 courses, the primary tumor showed a hypertrophic wall, but a partial response of the liver metastases (reduction ratio was 78.3%) and a complete response of the LN metastasis were achieved. PR and CR were maintained after 4 courses. There were no remarkable side effects for 4 courses. This chemotherapy may have therapeutic efficacy in cases of advanced gastric cancer with liver and lymph node metastases.
一例晚期胃癌伴多发肝转移患者经替吉奥（TS-1）和顺铂（CDDP）成功治疗：冢原晃洋、金子一弘、田中修司（新潟县小出医院外科）摘要 一名70岁的晚期胃癌患者伴有肝和淋巴结转移，接受了替吉奥和顺铂化疗。一个疗程包括给予替吉奥100mg/体，持续21天，随后休息14天，并在第8天输注顺铂80mg/体。在2个疗程结束时，原发肿瘤显示壁增厚，但肝转移灶出现部分缓解（缩小率为78.3%），淋巴结转移灶达到完全缓解。4个疗程后部分缓解（PR）和完全缓解（CR）得以维持。4个疗程均无明显副作用。这种化疗可能对伴有肝和淋巴结转移的晚期胃癌病例具有治疗效果。
