Suzuki Koji, Kawachi Sadaomi, Sakai Hiroshi, Nanke Hideki, Morita Sadao
Department of Orthopaedic Surgery, Toride Kyodo General Hospital, 2-1-1 Hongo, Toride 302-0022, Japan.
J Orthop Sci. 2004;9(6):571-5. doi: 10.1007/s00776-004-0830-3.
In this study, we used laboratory data and clinical outcomes to evaluate the degree of approach-related trauma in mini-incision arthroplasty. In 94 patients (8 male and 86 female), a total of 100 osteoarthritic joints were replaced using total hip arthroplasty (THA). The level of serum C-reactive protein (CRP) and the erythrocyte sedimentation rate (ESR) were measured 1 week postoperatively in both the standard group and a mini-incision group. The serum CRP level (mean +/- standard deviation) was 3.3 +/- 2.6 mg/dl in the standard incision group compared to 1.8 +/- 1.2 in the mini-incision group. The ESR level was 66 +/- 22 mm/h in the standard incision group and 52 +/- 20 mm/h in the mini-incision group. The ratio of the level of creatine phosphokinase (CPK) measured postoperatively/preoperatively was 4.7 on the first postoperative day in the standard incision group and 3.6 in the mini-incision group. On the basis of the CRP and ESR levels, the mini-incision THA was considered to be less invasive. However, there was no significant difference in the day 1 CPK ratios between the two groups, suggesting that the degree of muscle trauma was similar.
在本研究中，我们使用实验室数据和临床结果来评估微创关节成形术中与手术入路相关的创伤程度。94例患者（8例男性和86例女性）共100个骨关节炎关节接受了全髋关节置换术（THA）。在标准组和微创组术后1周测量血清C反应蛋白（CRP）水平和红细胞沉降率（ESR）。标准切口组血清CRP水平（均值±标准差）为3.3±2.6mg/dl，而微创组为1.8±1.2mg/dl。标准切口组ESR水平为66±22mm/h，微创组为52±20mm/h。术后/术前测量的肌酸磷酸激酶（CPK）水平比值在标准切口组术后第1天为4.7，微创组为3.6。基于CRP和ESR水平，微创全髋关节置换术被认为创伤较小。然而，两组术后第1天的CPK比值无显著差异，表明肌肉创伤程度相似。
