Cybistax antisyphilitica对埃及伊蚊幼虫的杀幼虫活性。
Larvicidal activity of Cybistax antisyphilitica against Aedes aegypti larvae.
作者信息
Rodrigues A M S, de Paula J E, Roblot F, Fournet A, Espíndola L S
机构信息
Laboratório de Farmacognosia, Faculdade de Ciências da Saúde, Universidade de Brasília, Brasília, Brazil.
出版信息
Fitoterapia. 2005 Dec;76(7-8):755-7. doi: 10.1016/j.fitote.2005.08.015. Epub 2005 Oct 17.
The larvicidal activity against Aedes aegypti larvae of a stem wood hexane extract of Cybistax antisyphilitica was evaluated. Bioassay-guided fractionation of the crude extract, monitored by larvicidal assay, led to the isolation of a natural quinone identified as 2-hydroxy-3-(3-methyl-2-butenyl)-1.4-naphthoquinone (lapachol). This compound was quite potent against A. aegypti larvae (LC50 26.3 microg/ml).
对赛比斯塔克斯抗梅毒树茎木己烷提取物针对埃及伊蚊幼虫的杀幼虫活性进行了评估。通过杀幼虫试验监测，对粗提物进行生物测定导向的分级分离，从而分离出一种天然醌，鉴定为2-羟基-3-(3-甲基-2-丁烯基)-1,4-萘醌（拉帕醇）。该化合物对埃及伊蚊幼虫具有相当强的活性（半数致死浓度为26.3微克/毫升）。
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