Department of Urology, National Cancer Center, Goyang, Gyeonggi, South Korea.
Departments of Biostatistics, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, Florida, United States of America.
PLoS One. 2014 Jan 21;9(1):e84938. doi: 10.1371/journal.pone.0084938. eCollection 2014.
Patients can experience urinary retention (UR) after Holmium laser enucleation of the prostate (HoLEP) that requires bladder distension during the procedure. The aim of this retrospective study is to identify factors affecting the UR after HoLEP.
336 patients, which underwent HoLEP for a symptomatic benign prostatic hyperplasia between July 2008 and March 2012, were included in this study. Urethral catheters were routinely removed one or two days after surgery. UR was defined as the need for an indwelling catheter placement following a failure to void after catheter removal. Demographic and clinical parameters were compared between the UR (n = 37) and the non-urinary retention (non-UR; n = 299) groups.
The mean age of patients was 68.3 (±6.5) years and the mean operative time was 75.3 (±37.4) min. Thirty seven patients (11.0%) experienced a postoperative UR. UR patients voided catheter free an average of 1.9 (±1.7) days after UR. With regard to the causes of UR, 24 (7.1%) and 13 (3.9%) patients experienced a blood clot-related UR and a non-clot related UR respectively. Using multivariate analysis (p<0.05), we found significant differences between the UR and the non-UR groups with regard to a morcellation efficiency (OR 0.701, 95% CI 0.498-0.988) and a bleeding-related complication, such as, a reoperation for bleeding (OR 0.039, 95% CI 0.004-0.383) or a transfusion (OR 0.144, 95% CI 0.027-0.877). Age, history of diabetes, prostate volume, pre-operative post-void residual, bladder contractility index, learning curve, and operative time were not significantly associated with the UR (p>0.05).
De novo UR after HoLEP was found to be self-limited and it was not related to learning curve, patient age, diabetes, or operative time. Efficient morcellation and careful control of bleeding, which reduces clot formation, decrease the risk of UR after HoLEP.
在经尿道钬激光前列腺剜除术(HoLEP)中,由于手术过程中需要膀胱扩张,患者可能会出现尿潴留(UR)。本回顾性研究旨在确定影响 HoLEP 后 UR 的因素。
2008 年 7 月至 2012 年 3 月期间,336 例接受 HoLEP 治疗的症状性良性前列腺增生患者纳入本研究。术后常规在 1-2 天拔除导尿管。UR 定义为拔除导尿管后未能自行排尿而需要留置导尿管。对 UR 组(n=37)和非尿潴留(non-UR;n=299)组的人口统计学和临床参数进行比较。
患者的平均年龄为 68.3(±6.5)岁,平均手术时间为 75.3(±37.4)分钟。37 例患者(11.0%)术后出现 UR。UR 患者平均在 UR 后 1.9(±1.7)天可以自行排尿,无需留置导尿管。UR 患者中,24 例(7.1%)和 13 例(3.9%)分别因血块相关和非血块相关 UR 而出现 UR。多因素分析(p<0.05)发现,UR 组与 non-UR 组在碎石效率(OR 0.701,95%CI 0.498-0.988)和与出血相关的并发症(如因出血再次手术,OR 0.039,95%CI 0.004-0.383;或输血,OR 0.144,95%CI 0.027-0.877)方面存在显著差异。年龄、糖尿病史、前列腺体积、术前残余尿量、膀胱收缩力指数、学习曲线和手术时间与 UR 无显著相关性(p>0.05)。
HoLEP 术后新发 UR 为自限性,与学习曲线、患者年龄、糖尿病或手术时间无关。高效碎石和仔细控制出血,减少血块形成,可降低 HoLEP 后 UR 的风险。