Reece E A
Department of Obstetrics, Gynecology, and Reproductive Sciences, Temple University School of Medicine, Philadelphia, PA 19140.
Curr Opin Obstet Gynecol. 1992 Jun;4(3):447-55.
Embryoscopy is a new technique that allows direct visualization of the embryo/fetus as early as the first trimester. A rigid fiberoptic endoscope is passed transcervically into the extracoelomic cavity and has been utilized to identify developmental milestones from weeks 4 to 8 following conception. All major external and internal structures develop during this period. With this technique, it is possible to both identify anomalies and confirm those diagnosed by ultrasound. Fetal blood sampling has also been preformed utilizing this technology and has established the feasibility of access to the human embryonic circulation. Future applications for embryoscopy include first-trimester prenatal diagnosis and therapeutic interventions such as gene or cell therapy at a time when the embryo is immunologically tolerant.
胚胎镜检查是一项新技术，最早在孕早期即可直接观察胚胎/胎儿。一根硬性光纤内窥镜经宫颈插入体腔外，已被用于识别受孕后第4至8周的发育里程碑。在此期间，所有主要的外部和内部结构都在发育。通过这项技术，既可以识别异常情况，也可以确认超声诊断出的异常情况。利用这项技术还进行了胎儿血液采样，并证实了进入人类胚胎循环的可行性。胚胎镜检查的未来应用包括孕早期产前诊断以及在胚胎具有免疫耐受性时进行基因或细胞治疗等治疗干预。
