Ville Y, Khalil A, Homphray T, Moscoso G
Fetal Medicine Unit, St George's Hospital, London, U.K.
Prenat Diagn. 1997 Dec;17(13):1237-46.
Embryoscopy is the examination of the embryo at 9-10 weeks' gestation through the intact membranes by introducing an endoscope into the exocoelomic space transcervically or transabdominally. This is likely to remain confined to the management of early pregnancy in selected families affected by recurrent genetic syndromes with recognizable external fetal abnormalities. The procedure-related risk of fetal loss is around 12 per cent. Fetoscopy is the examination of the fetus after 11 weeks' gestation. This is performed transabdominally in the amniotic fluid. The technique has evolved with the miniaturization of the optical device by using fibre-optics technology. This procedure is likely to find new applications with the development of ultrasound examination at 10-14 weeks' gestation in order to, either confirm, or rule out suspected external fetal abnormalities. Amniocentesis can be performed at the same time. The procedure-related risk is likely to remain below 10 per cent but no accurate figures can be drawn from the literature.
胚胎镜检查是在妊娠9至10周时，通过完整的胎膜，经宫颈或经腹将内窥镜插入胚外体腔对胚胎进行检查。这可能仍局限于受复发性遗传综合征影响且胎儿有可识别的外部异常的特定家庭的早期妊娠管理。与该操作相关的胎儿丢失风险约为12%。胎儿镜检查是在妊娠11周后对胎儿进行检查。这是经腹在羊水中进行的。随着光纤技术使光学设备小型化，该技术也得到了发展。随着妊娠10至14周超声检查的发展，该操作可能会有新的应用，以便确认或排除可疑的胎儿外部异常。同时可以进行羊膜穿刺术。与该操作相关的风险可能仍低于10%，但从文献中无法得出准确数字。
