Anderson Laura L, Arnold John, Bergman Robert G
Department of Chemistry, University of California, Berkeley, California 94720, USA.
J Am Chem Soc. 2005 Oct 26;127(42):14542-3. doi: 10.1021/ja053700i.
The anilinium salt, [PhNH3][B(C6F5)4], has been identified as a catalyst for the hydroamination and hydroarylation of several different types of alkenes with anilines. The weakly coordinating counterion of this acid plays a key role in this transformation. The reaction is facile for styrenes and tolerates norbornene, cyclic alkenes, and cyclohexadiene. Selectivity between hydroamination and hydroarylation products can be tuned using reaction time, temperature, and substrate substitution. Details regarding the substrate scope and selectivity of this hydroamination/hydroarylation reaction are discussed.
苯胺盐[PhNH₃][B(C₆F₅)₄]已被确定为几种不同类型烯烃与苯胺进行氢胺化和氢芳基化反应的催化剂。这种酸的弱配位抗衡离子在该转化过程中起关键作用。该反应对苯乙烯很容易进行,并且能耐受降冰片烯、环状烯烃和环己二烯。可以通过反应时间、温度和底物取代来调节氢胺化产物和氢芳基化产物之间的选择性。本文讨论了该氢胺化/氢芳基化反应的底物范围和选择性的详细情况。