帕金森病的发病机制。
Pathogenesis of Parkinson's disease.
作者信息
Riederer P, Lange K W
机构信息
Department of Clinical Neurochemistry, University Hospital for Nervous Diseases, University of Würzburg, Germany.
出版信息
Curr Opin Neurol Neurosurg. 1992 Jun;5(3):295-300.
PMID:1623255
Abstract
The importance of genetic aspects, ageing, environmental factors, head trauma, defective mitochondrial respiration, altered iron metabolism, oxidative stress and glutamatergic overactivity of the basal ganglia in the pathogenesis of Parkinson's disease (PD) are considered in this review.
摘要
本文综述了遗传因素、衰老、环境因素、头部创伤、线粒体呼吸缺陷、铁代谢改变、氧化应激以及基底神经节谷氨酸能活性过强在帕金森病（PD）发病机制中的重要性。
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