Granström Tom Birger, Takata Goro, Tokuda Masaaki, Izumori Ken
Rare Sugar Research Center, Kagawa University, Kagawa 761-0795, Japan.
J Biosci Bioeng. 2004;97(2):89-94. doi: 10.1016/S1389-1723(04)70173-5.
Starch, whey or hemicellulosic waste can be used as a raw material for the industrial production of rare sugars. D-glucose from starch, whey and hemicellulose, D-galactose from whey, and D-xylose from hemicellulose are the main starting monosaccharides for production of rare sugars. We can produce all monosaccharides; tetroses, pentoses and hexoses, from these raw materials. This is achieved by using D-tagatose 3-epimerase, aldose isomerase, aldose reductase, and oxidoreductase enzymes or whole cells as biocatalysts. Bioproduction strategies for all rare sugars are illustrated using ring form structures given the name Izumoring.
淀粉、乳清或半纤维素废料可用作工业生产稀有糖的原料。来自淀粉、乳清和半纤维素的D-葡萄糖、来自乳清的D-半乳糖以及来自半纤维素的D-木糖是生产稀有糖的主要起始单糖。我们可以从这些原料生产所有单糖,包括丁糖、戊糖和己糖。这是通过使用D-塔格糖3-差向异构酶、醛糖异构酶、醛糖还原酶和氧化还原酶或全细胞作为生物催化剂来实现的。使用名为“和光环”的环状结构说明了所有稀有糖的生物生产策略。