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胺碘酮治疗新生儿复发性室上性心动过速:高钾血症是明显病因吗?

Recurrent supraventricular tachycardia in a newborn treated with amiodarone: is hyperkalemia the apparent cause?

作者信息

Yildirim S V, Tiker F, Cengiz N, Kiliçdağ H

机构信息

Division of Pediatric Cardiology, Baskent University, Adana Teaching and Medical Research Center, Kurtuluş Mah. 13.sk. Egemert Apt., Kat: 3, Daire No: 7, Adana, Turkey.

出版信息

Pediatr Cardiol. 2005 Nov-Dec;26(6):879-80. doi: 10.1007/s00246-005-1043-z.

DOI:10.1007/s00246-005-1043-z
PMID:16235017
Abstract

Supraventricular tachycardia (SVT) is the most common type of arrhythmia observed in children, especially in newborns. Infants with severe SVT must be treated immediately with first-line drugs such as amiodarone. There are some minor and major side effects of amiodarone in this patient group, but no associated electrolyte disorders have been observed. This report describes a newborn whose recurrent SVT attacks during amiodarone treatment were suspected to have been caused by hyperkalemia.

摘要

室上性心动过速(SVT)是儿童尤其是新生儿中最常见的心律失常类型。患有严重室上性心动过速的婴儿必须立即使用胺碘酮等一线药物进行治疗。在该患者群体中,胺碘酮存在一些轻微和严重的副作用,但未观察到相关的电解质紊乱。本报告描述了一名新生儿,其在胺碘酮治疗期间反复发作的室上性心动过速被怀疑是由高钾血症引起的。

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Recurrent supraventricular tachycardia in a newborn treated with amiodarone: is hyperkalemia the apparent cause?胺碘酮治疗新生儿复发性室上性心动过速:高钾血症是明显病因吗?
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Side effects of long-term amiodarone therapy.长期胺碘酮治疗的副作用。
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The influence of potassium concentration on the inhibitory effect of amiodarone on guinea-pig microsomal Na(+)-K(+)-ATPase activity.钾离子浓度对胺碘酮抑制豚鼠微粒体钠钾ATP酶活性作用的影响
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