胺碘酮治疗胎儿室上性心动过速。一例病例报告及文献综述。

Amiodarone in treatment of fetal supraventricular tachycardia. A case report and review of literature.

作者信息

Pradhan Mandakini, Manisha Mrs, Singh Renu, Kapoor Aditya

机构信息

Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, U.P., India.

出版信息

Fetal Diagn Ther. 2006;21(1):72-6. doi: 10.1159/000089052.

DOI:10.1159/000089052

PMID:16354980

Abstract

We report a case of nonimmune hydrops fetalis detected at 32 weeks of gestation. Fetal heart rate was 300 beats per minute. Ultrasound and fetal Doppler echocardiography showed it to be due to supraventricular tachycardia (SVT). Following failed maternal therapy with digoxin alone, amiodarone with digoxin was used. Conversion to sinus rhythm and resolution of hydrops followed this treatment. Since there is no ideal treatment protocol for these cases at present, we reviewed reports of transplacental treatment of SVT.

摘要

我们报告一例在妊娠32周时检测到的非免疫性胎儿水肿病例。胎儿心率为每分钟300次。超声和胎儿多普勒超声心动图显示这是由于室上性心动过速（SVT）所致。在母亲单独使用地高辛治疗失败后，联合使用了胺碘酮和地高辛。经此治疗后转为窦性心律，胎儿水肿消退。由于目前尚无针对这些病例的理想治疗方案，我们回顾了经胎盘治疗室上性心动过速的报告。