Cirla P E, Martinotti I, Zito E, Prandi E, Buratti M, Longhi O, Fustinoni S, Cavallo D, Ariano E, Cantoni S, Foà V
Università degli Studi di Milano, Dipartimento di Medicina del Lavoro, Milano.
G Ital Med Lav Ergon. 2005 Jul-Sep;27(3):303-7.
Asphalt is a mixture of mineral matter and bitumen, its fumes contain about 1% of Polycyclic Aromatic Hydrocarbons (PAH), some of which are carcinogens. In the PPTP-POPA Study of Lombardy Region, a group of 100 asphalt workers (exposed to bitumen fumes and diesel exhausts) and a group of 47 ground construction operators (exposed only to diesel exhausts) were investigated to assess PAH exposure in Italy, by means of environmental-air monitoring (the 16 most relevant, according to the American Environmental Protection Agency, EPA) and biological monitoring (urinary 1-hydroxypyrene excretion). Our results show that PAH exposure in these workers is not higher than that observed in traffic policemen working in urban areas. Since dermal exposure has been suggested as a major determinant of the total PAH dose absorbed by road pavers from bitumen fumes, we assessed skin contamination by organic aromatic compounds and by sixteen PAH: in both groups, six pads were applied to each subject in different parts of the body, during the workshift. The results show that the dermal contamination in road pavers is higher than in ground construction operators and that cutaneous dose rate is higher than respiratory dose rate, whereas the amount of absorption the ratio is inverted.
沥青是矿物质和沥青的混合物,其烟雾中含有约1%的多环芳烃(PAH),其中一些是致癌物。在伦巴第地区的PPTP - POPA研究中,对一组100名沥青工人(暴露于沥青烟雾和柴油废气中)和一组47名地面建筑工人(仅暴露于柴油废气中)进行了调查,以通过环境空气监测(根据美国环境保护局(EPA)列出的16种最相关物质)和生物监测(尿中1 - 羟基芘排泄量)来评估意大利的PAH暴露情况。我们的结果表明,这些工人的PAH暴露水平并不高于在城市地区工作的交通警察所观察到的水平。由于皮肤接触被认为是铺路工人从沥青烟雾中吸收的总PAH剂量的主要决定因素,我们评估了有机芳香化合物和16种PAH对皮肤的污染情况:在两个组中,在工作班次期间,在每个受试者身体的不同部位贴了6个垫子。结果表明,铺路工人的皮肤污染程度高于地面建筑工人,皮肤剂量率高于呼吸剂量率,而吸收量的比例则相反。