Giordano Nicola, Amendola Alessandra, Papakostas Panayotis, Cipolli Fiorenza, Agate Vita Maria, Martini Giuseppe, Figura Natale, Nuti Ranuccio
Department of Internal Medicine, Endocrine-Metabolic Sciences and Biochemistry, University of Siena, Italy.
New Microbiol. 2005 Jul;28(3):261-3.
Human immunodeficiency virus (HIV) infection can be associated with many autoimmune disorders such as antiphospholipid antibody syndrome. The most common neurologic complication is represented by peripheral neuropathies, but its pathogenesis is still unknown. We report the clinical case of a 44-year-old woman with HIV infection, peripheral polyneuropathy and arterial thrombosis, in which high serum levels of antiphospholipid antibodies were repeatedly documented. We suggest that the evaluation of serum antiphospholipid antibodies levels in HIV infection is fundamental both from an exploratory point of view and for starting the best treatment.
人类免疫缺陷病毒（HIV）感染可能与许多自身免疫性疾病相关，如抗磷脂抗体综合征。最常见的神经并发症是周围神经病变，但其发病机制仍不清楚。我们报告了一例44岁感染HIV的女性病例，该患者患有周围性多发性神经病和动脉血栓形成，多次检测发现其血清抗磷脂抗体水平升高。我们认为，从探索性角度以及开始最佳治疗方面来看，评估HIV感染患者的血清抗磷脂抗体水平至关重要。
