Pompili Maurizio, Mancinelli Iginia, Ruberto Amedeo, Kotzalidis Giorgio D, Girardi Paolo, Tatarelli Roberto
Sant'Andrea Hospital, University of Rome La Sapienza, Psichiatria, Italy.
Int J Psychiatry Med. 2005;35(2):171-90. doi: 10.2190/9CA1-EL73-1VXD-9F2V.
To review the literature on suicide of inpatients with schizophrenia, to identify suicide risk factors as well as typical patterns of behavior and to suggest a rationale and strategies for future interventions.
A computerized MedLine, Excerpta Medica and PsycLit search supplemented by an examination of cross-references and reviews.
Up to half the suicides among patients with schizophrenia occur during inpatient admission. Inpatient suicides were found among those of a young age group who were predominantly single, childless and socially isolated. The vast majority experienced an illness characterized by long duration and prolonged psychiatric hospitalizations or multiple admissions and discharges. Up to 50% of the suicides occurred in the first few weeks and months following discharge from the hospital. The paranoid subtype of schizophrenia, where positive symptoms prevail and negative symptoms are few, is associated with a suicide risk that is three times greater than that associated with nonparanoid subtypes and eight times greater than the risk associated with the deficit subtype.
Treatment of suicide is a major problem among inpatients with schizophrenia. Evidence suggests that suicide is generally carried-out by patients who have been recently discharged or by those who manage to get away from the hospital. Strategies aimed at preventing this phenomenon have been introduced to the medical personnel, but suicide in these patients does not seem to have been reduced. We emphasize the need to establish guidelines for the prevention of suicide in hospitalized patients with schizophrenia.
回顾关于精神分裂症住院患者自杀的文献,确定自杀风险因素以及典型行为模式,并提出未来干预的基本原理和策略。
通过计算机检索医学在线数据库(MedLine)、医学文摘数据库(Excerpta Medica)和心理学文献数据库(PsycLit),并辅以交叉引用检查和综述。
精神分裂症患者中高达一半的自杀发生在住院期间。住院自杀者多为年轻群体,主要是单身、无子女且社会孤立的人。绝大多数患者患有病程长、多次住院或反复出入院的疾病。高达50%的自杀发生在出院后的头几周和几个月内。以阳性症状为主且阴性症状较少的偏执型精神分裂症患者的自杀风险是非偏执型的三倍,是衰退型的八倍。
自杀治疗是精神分裂症住院患者的一个主要问题。有证据表明,自杀通常由近期出院的患者或设法逃离医院的患者实施。已向医务人员介绍了旨在预防这一现象的策略,但这些患者的自杀率似乎并未降低。我们强调需要为住院精神分裂症患者制定预防自杀的指导方针。