Portin P, Rantanen M
Department of Biology, University of Turku, Finland.
Genetica. 1992;85(2):147-51. doi: 10.1007/BF00120321.
A selective method was developed, based on negative complementation of the Abruptex alleles of the Notch locus, for studying primary sex chromosome non-disjunction in females and males of Drosophila melanogaster and X-Y exchange in males. The results show that the frequency of primary non-disjunction of structurally normal X chromosomes was lower than the frequency of X-derY non-disjunction in males. Double exchange between the X and the derY chromosome in the male occurs with a frequency of at least 0.091%. Single exchanges are naturally expected to occur with even higher frequency. Exchanges were interestingly at least partly of euchromatic nature. The origin of these exchanges is at least partly of gonial origin.
基于Notch基因座的Abruptex等位基因的负互补作用，开发了一种选择性方法，用于研究黑腹果蝇雌性和雄性中的原发性性染色体不分离以及雄性中的X-Y交换。结果表明，结构正常的X染色体原发性不分离的频率低于雄性中X-derY不分离的频率。雄性中X染色体与derY染色体之间的双交换频率至少为0.091%。自然预期单交换的发生频率会更高。有趣的是，这些交换至少部分是常染色质性质的。这些交换的起源至少部分是生殖细胞起源的。
