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Frequent varicella zoster reactivation associated with therapeutic use of arsenic trioxide: portents of an old scourge.

作者信息

Au Wing-Yan, Kwong Yok-Lam

机构信息

University Department of Medicine, Queen Mary Hospital, Hong Kong.

出版信息

J Am Acad Dermatol. 2005 Nov;53(5):890-2. doi: 10.1016/j.jaad.2005.07.030.

DOI:10.1016/j.jaad.2005.07.030
PMID:16243151
Abstract

In 44 patients treated with arsenic trioxide (As2(O3)) for acute promyelocytic leukemia, 11 developed varicella zoster virus (VZV) reactivation (median 56 days [range 15-299]) after treatment. There was no preferential dermatome involvement or systemic spread. The actuarial risk of VZV reactivation at 1 year was 26%. No VZV reactivation occurred after the first year of initial treatment with As2(O3).

摘要

相似文献

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