Howard B R
Field Laboratories, University of Sheffield, Medical School, United Kingdom.
J Am Vet Med Assoc. 1992 Jun 1;200(11):1667-74.
Each week over a 6-week period, 80 adult cockatiels (Nymphicus hollandicus) of either gender were dosed orally with fine particles of pure zinc or galvanized coating removed from welded wire mesh. At dosage of 32 mg/wk, all birds became severely ill and either died or were euthanatized within 2 weeks. Dosage of 2 mg/wk induced chronic illness marked by dullness, weight loss, and intermittent excretion of greenish droppings. Necropsy findings were unremarkable, except for signs suggestive of impaired gastrointestinal tract motility and histologic degenerative changes associated with focal mononuclear infiltration in the liver, kidneys, and pancreas. Tissue, especially pancreatic, contents of zinc were markedly high. Pure zinc was as toxic as galvanizing zinc. White rust, an oxidation product, also was toxic. The galvanized coating on cages and flights must be carefully wirebrushed and examined before housing psittacine birds.
在为期6周的时间里，每周给80只成年鸡尾鹦鹉（虎皮鹦鹉）口服从电焊网上去除的纯锌细颗粒或镀锌涂层，无论雌雄。在每周32毫克的剂量下，所有鸟类都患上重病，在2周内死亡或被安乐死。每周2毫克的剂量会引发慢性病，表现为精神萎靡、体重减轻和间歇性排出绿色粪便。尸检结果无明显异常，只是有提示胃肠道蠕动受损的迹象，以及肝脏、肾脏和胰腺中与局灶性单核细胞浸润相关的组织学退行性变化。组织中，尤其是胰腺中的锌含量明显很高。纯锌与镀锌锌一样有毒。白色锈迹，一种氧化产物，也有毒性。在饲养鹦鹉类鸟类之前，必须仔细用钢丝刷清理并检查笼子和鸟舍上的镀锌涂层。
